Petunidin 3-O-glucoside is an anthocyanin that has been found in red grapes and red wines with antiproliferative properties. It reduces DBTRG-05MG glioblastoma cell growth in a time- and concentration-dependent manner by increasing production of reactive oxygen species (ROS) and Bax protein levels and reducing Bcl-2 and caspase-3 activities. Petunidin 3-O-glucoside also reduces glucose uptake, lactic acid production, and NAD levels in DBTRG-05MG cells.
