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ChemicalBook > CAS DataBase List > Memantine HCl

Memantine HCl

  • $14 - $860
  • Product name:Memantine HCl
  • CAS:41100-52-1
  • MF: C12H22ClN
  • MW:215.76
  • EINECS:255-219-6
  • MDL Number:MFCD00214336
  • Synonyms:MEMANTINE HCL;LABOTEST-BB LT00233220;1,3-Dimethyl-5-aminoadamantane hydrochloride;1,3-DIMETHYLAMINOADAMANTANE HYDROCHLORIDE;1-AMINO-3,5-DIMETHYLADAMANTANE HCL;1-AMINO-3,5-DIMETHYLADAMANTANE HYDROCHLORIDE;1-AMINO-3,4-DIMETHYLADAMANTANE HYDROCHLORIDE;3,5-DIMETHYLAMANTADINE HYDROCHLORIDE
Price
  • Brand:TCI Chemical
  • Product number:D3608
  • Product name3,5-Dimethyl-1-adamantanamine Hydrochloride
  • Purity:>98.0%(N)(T)
  • Packaging:25g
  • Price:$86
  • Updated:2021/12/16 16:57:17
  • Buy:Buy
  • Brand:TCI Chemical
  • Product number:D3608
  • Product name3,5-Dimethyl-1-adamantanamine Hydrochloride
  • Purity:>98.0%(N)(T)
  • Packaging:5g
  • Price:$29
  • Updated:2021/12/16 16:57:17
  • Buy:Buy
  • Brand:Tocris
  • Product number:0773
  • Product nameMemantine hydrochloride
  • Purity:
  • Packaging:50
  • Price:$113
  • Updated:2021/12/16 17:17:49
  • Buy:Buy
  • Brand:TRC
  • Product number:M218000
  • Product nameMemantine hydrochloride
  • Purity:
  • Packaging:50mg
  • Price:$55
  • Updated:2021/12/16 17:17:49
  • Buy:Buy
  • Brand:TRC
  • Product number:M218000
  • Product nameMemantine hydrochloride
  • Purity:
  • Packaging:1g
  • Price:$415
  • Updated:2021/12/16 17:17:49
  • Buy:Buy
Properties
  • Melting point:292 °C
  • storage temp. Inert atmosphere,2-8°C
  • form Fine Powder
  • color White
  • Merck 14,5806
  • CAS DataBase Reference41100-52-1(CAS DataBase Reference)
Safety Information
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements
  • H315:Causes skin irritation
  • H319:Causes serious eye irritation
  • Precautionary statements
  • P264:Wash hands thoroughly after handling.
  • P264:Wash skin thouroughly after handling.
  • P280:Wear protective gloves/protective clothing/eye protection/face protection.

Description

Memantine HCl is the HCl form of Memantine. Memantine is a well- known neuroprotective drug used for the treatment of Alzheimer’s disease. It is believed to be the first neuroprotective drug that has achieve clinical approval by US FDA as well as European. The development of Alzheimer’s disease involves the misfolded mutant proteins such as β-amyloid peptide (Aβ, particularly Aβ1−42). These misfolded mutant protein can increase the NMDA response and further cause severe excitotoxicity. Memantine suppresses this process through acting as the antagonist of the N-methyl-d- aspartate-sensitive glutamate receptor (NMDARs). Memantine is also under investigation as a potential treatment for other kind of neurodegenerative disorders such as HIV-associated dementia, neuropathic pain, glaucoma, depression, Huntington’s disease, ALS and movement disorders, among other.


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