LysoBrite™ reagents are fluorogenic probes that can be used to label lysosomes within live cells. They are hydrophobic and easily cross live cell membranes to accumulate in lysosomes likely via the lysosomal pH gradient. LysoBrite™ fluorescence is enhanced in the acidic environment within the lysosome, and this fluorescence can be measured using fluorescence microscopy, microplate fluorometry, or flow cytometry. LysoBrite™ Deep Red exhibits excitation/emission maxima of 596/619 nm, respectively. It has been used as a lysosome marker to study the localization of hypochlorous acid (HOCl) in live cells.1WARNING This product is not for human or veterinary use.
