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Linsitinib
Linsitinib
$28 - $4173.5
Product name
Linsitinib
Cas No
867160-71-2
MF
C26H23N5O
MW
421.49
EINECS
1533716-785-6
MDL Number
MFCD12912153
Synonyms
cis-3-[8-Amino-1-(2-phenyl-7-quinolinyl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutanol;Linsitinib;OSI-906 Linsitinib;Cyclobutanol, 3-[8-aMino-1-(2-phenyl-7-quinolinyl)iMidazo[1,5-a]pyrazin-3-yl]-1-Methyl-, cis-;OSI 906AA;(1S,3r)-3-((S)-8-aMino-1-(2-phenylquinolin-7-yl)-2,3-dihydroiMidazo[1,5-a]pyrazin-3-yl)-1-Methylcyclobutanol;(1s,3r)-3-[4-aMino-3-(2-phenylquinolin-7-yl)iMidazo[1,5-a]pyrazin-1-yl]-1-Methylcyclobutan-1-ol;Linsitinib, Free Base
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Price
33 prices
Brand
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Cayman Chemical
Arctom
Crysdot
TRC
Usbiological
Biorbyt Ltd
ApexBio Technology
AK Scientific
Medical Isotopes, Inc.
ChemScene
American Custom Chemicals Corporation
Biosynth Carbosynth
DC Chemicals
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1unit
1mg
5mg
10mg
20mg
25mg
50mg
100mg
200mg
250mg
300mg
500mg
1g
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Brand
Packaging
Price
Product name
AK Scientific
SYN5696
100mg
$567
OSI-906
American Custom Chemicals Corporation
KIN0000462
5MG
$816.75
OSI-906
American Custom Chemicals Corporation
KIN0000462
50MG
$2194.5
OSI-906
ApexBio Technology
A8334
1unit
$28
Linsitinib
Arctom
CFN60221
20mg
$268
Linsitinib(OSI-906)
Biorbyt Ltd
orb153620
5mg
$329.8
Linsitinib, Free Base
Biorbyt Ltd
orb153620
10mg
$362.1
Linsitinib, Free Base
Biorbyt Ltd
orb546256
50mg
$380.8
Linsitinib
Biorbyt Ltd
orb153620
25mg
$447.1
Linsitinib, Free Base
Biorbyt Ltd
orb546256
10mg
$173.4
Linsitinib
1
of
4
Properties
Melting point
>175°C (dec.)
Density
1.39
storage temp.
-20°C
solubility
Soluble in DMSO (up to 30 mg/ml)
form
solid
pka
14.84±0.40(Predicted)
color
Yellow
Stability
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
InChIKey
PKCDDUHJAFVJJB-VLZXCDOPSA-N
SMILES
[C@]1(C)(O)C[C@H](C2N3C=CN=C(N)C3=C(C3C=C4C(=CC=3)C=CC(C3=CC=CC=C3)=N4)N=2)C1
Description
Linsitinib (OSI-906) is a selective inhibitor of IGF-1R with IC50 of 35 nM in cell-free assays; modestly potent to InsR with IC50 of 75 nM, and no activity towards Abl, ALK, BTK, EGFR, FGFR1/2, PKA etc. Phase 3.
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Suppliers and manufacturers
career henan chemical co
$6.68
/1KG
Linsitinib
CAS:867160-71-2
Capot Chemical Co.,Ltd.
ATK CHEMICAL COMPANY LIMITED
Biochempartner
Changzhou PBpharmaceutical R&D Co.,Ltd
CONIER CHEM AND PHARMA LIMITED
Dideu Industries Group Limited
Zhejiang J&C Biological Technology Co.,Limited
Henan Alfa Chemical Co., Ltd
InvivoChem
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