Ketamine hydrochloride

The receptor for N-methyl-D-aspartate (NMDA) is a glutamate-gated ion channel that has key roles in synaptic plasticity, memory acquisition, hyperalgesia, and allodynia. Ketamine is an NMDA receptor channel blocker (Ki = 1.2-2.5 μM, IC50 = 3.2-6.1 μM). It is a dissociative anesthetic that has analgesic properties at subanesthetic doses. Ketamine and its analog methoxetamine are abused recreationally. Ketamine is regulated as a Schedule III compound in the United States. This product is intended for forensic and research purposes.

This product is a qualified Reference Material (RM) that has been manufactured and tested to meet ISO17025 and Guide 34 guidelines. These materials are tested using validated analytical methods on qualified instrumentation to ensure traceability of measurements. All traceable RMs may be distinguished by their CofAs and can be downloaded below using the batch number located on the product label. For a representative CofA please contact our technical support.