≥27.4 mg/mL in DMSO; insoluble in H2O; ≥51.2 mg/mL in EtOH
form
powder
color
white to beige
Description
KU-60019 is an improved analogue of KU-55933, with IC50 of 6.3 nM for ATM in cell-free assays, 270- and 1600-fold more selective for ATM than DNA-PK and ATR,and is a highly effective radiosensitizer.
