P305+P351+P338：IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
Description
FH535 is an inhibitor of β-catenin/Tcf-mediated transcription and an antagonist of ligand-dependent activation of PPARγ and PPARδ. At 15 μM, FH535 blocks the recruitment of β-catenin and GRIP1 to PPARγ and PPARδ. Presumably through these actions, FH535 is selectively toxic to some carcinoma cell lines expressing the Wnt/β-catenin pathway. FH535 is used to study the role of Wnt/β-catenin pathway in various cancer cell lines.
