P270:Do not eat, drink or smoke when using this product.
P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P405:Store locked up.
P501:Dispose of contents/container to..…
Description
Epinastine is a non-sedating ophthalmic antihistamine that antagonizes histamine H1 receptors (IC50 = 1.58 nM in guinea pigs) and prevents the release of pro-inflammatory mediators from mast cells and eosinophils. Although it can pass through the blood-brain barrier, the low brain distribution of epinastine is accounted for by efficient efflux transport by P-glycoproteins and poor uptake by the influx transporter. Epinastine also inhibits superoxide generation by rat neutrophils.