T863 has been used as a diglyceride acyltransferase (DGAT1) inhibitor:
- to provide the opportunity to precisely control the DGAT inhibition
- to treat mouse embryonic fibroblasts (MEFs) to analyse lipid droplet biogenesis
- to specifically block neutral?lipid synthesis?and lipid droplet formation in HT-1080 cells
- to block lipid droplet (LD) formation