Dextrorphan is a phencyclidine-like metabolite of dextromethorphan , an antitussive found in cough medicines. Dextrorphan, while also having antitussive activity, is psychoactive, leading to the abuse of cough medicines containing the parent compound. Dextrorphan antagonizes NMDA and μ-opioid receptors (Kis = 54 and 420 nM, respectively) and inhibits norepinephrine and serotonin transporters (Kis = 340 and 401 nM, respectively). This product is intended for forensic and research applications.
