P270:Do not eat, drink or smoke when using this product.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P403:Store in a well-ventilated place.
Description
Celiprolol is a β1 adrenergic receptor antagonist and a β2 adrenergic receptor partial agonist that has been shown to relax human arteries and veins with ED50 values of 40-50 μM in vitro. At 1-10 mg/kg/h, celiprolol can reduce myocardial infarct size and increase nitric oxide (NO) production in a rabbit model of myocardial ischemia. Furthermore, 100 mg/kg/d celiprolol has been reported to stimulate expression and activate phosphorylation of endothelial NO synthase in rat cardiac myocytes.