CYNARIN

$37 - $4631

Product nameCYNARIN
Cas No19870-46-3
MFC25H24O12
MW516.45
EINECS214-655-7
MDL NumberMFCD13196505

Synonyms

1,3-Dicaffeoylquinic acid;(1S,3R,4R,5R)-1,3-Bis[3-(3,4-dihydroxyphenyl)acryloyloxy]-4,5-dihydroxycyclohexanecarboxylic acid;Dicaffeoylquinic Acid, 1,5-;(1S,3R,4R,5R)-1,3-bis[[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy]-4,5-dihydroxycyclohexane-1-carboxylic acid;1,5-di-O-Caffeoylquinic acid;Cyclohexanecarboxylic acid, 1,3-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-4,5-dihydroxy-, (1S,3R,4R,5R)-;(1S,3R,4R,5R)-1,3-bis[[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy]-4,5-dihydroxycyclohexane-1-carboxylicaci;19870-46-3 CYNARIN

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Price

42 prices

Brand less more

Sigma-Aldrich Cayman Chemical CSNpharm Arctom Crysdot AvaChem TRC Biorbyt Ltd ApexBio Technology Matrix Scientific AK Scientific ChemScene American Custom Chemicals Corporation Biosynth Carbosynth
Package less more

1mlx10mm(indmso) 1mg 5mg 10mg 20mg 25mg 50mg 100mg 200mg 250mg 1g

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Brand	Packaging	Price	Product name
AK Scientific 0210AB	5mg	$284	1,3-O-Dicaffeoylquinicacid
American Custom Chemicals Corporation PXT0003565	5MG	$496.6	1,3-O-DICAFFEOYLQUINIC ACID
ApexBio Technology B8457	10mg	$251	1,3-Dicaffeoylquinic acid
ApexBio Technology B8457	5mg	$157	1,3-Dicaffeoylquinic acid
Arctom CFN90937	20mg	$198	1,3-Dicaffeoylquinicacid
Arctom SY232472	10mg	$300	Cynarin(1,3-Dicaffeoylquinicacid)
AvaChem 2087	10mg	$195	1,3-Dicaffeoylquinic acid
AvaChem 2087	5mg	$135	1,3-Dicaffeoylquinic acid
AvaChem 2087	100mg	$1075	1,3-Dicaffeoylquinic acid
Biorbyt Ltd orb1301539	10mg	$140	1,3-Dicaffeoylquinic acid

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Properties

Boiling point	819.9±65.0 °C(Predicted)
Density	1+-.0.1 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,2-8°C
solubility	soluble5mg/mL, clear, colorless to light yellow
form	Solid
pka	2.50±0.50(Predicted)
color	white to off-white
Stability	Hygroscopic
Major Application	food and beverages
InChIKey	YDDUMTOHNYZQPO-PSEXTPKNSA-N
SMILES	O[C@@H]1C[C@@](C[C@@H](OC(=O)\C=C\c2ccc(O)c(O)c2)[C@@H]1O)(OC(=O)\C=C\c3ccc(O)c(O)c3)C(O)=O

Safety Information

Symbol(GHS)

Signal word

Warning

Hazard statements

H315：Causes skin irritation

H319：Causes serious eye irritation

Precautionary statements

P261：Avoid breathing dust/fume/gas/mist/vapours/spray.

P264：Wash hands thoroughly after handling.

P264：Wash skin thouroughly after handling.

P270：Do not eat, drink or smoke when using this product.

P271：Use only outdoors or in a well-ventilated area.

P280：Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338：IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313：IF SKIN irritation occurs: Get medical advice/attention.

P337+P313：IF eye irritation persists: Get medical advice/attention.

P501：Dispose of contents/container to..…

Description

1,5-Dicaffeoylquinic acid (1,5-DCQA) has been found in A. montana and is an HIV-1 integrase inhibitor and free radical scavenger. 1,5-DCQA inhibits HIV-1 integrase 3'' end processing, end joining, and disintegration with IC₅₀ values of 0.35, 0.56, and 0.84 μg/ml, respectively. It also inhibits HIV-1 replication in MT-2 T lymphoblastoid cells with an ED₅₀value of 2 μg/ml. 1,5-DCQA (0.25-1 μM) reduces the level of free radicals released from human polymorphonuclear (PMN) cells stimulated by N-formyl-Met-Leu-Phe (fMLP; ) in a dose-dependent manner. It also dose-dependently increases cell survival and glutathione (GSH) levels and decreases reactive oxygen species (ROS) production and lactate dehydrogenase (LDH) release in an oxygen-glucose deprivation/reperfusion assay in rat cerebral astrocytes when used at concentrations ranging from 5 to 100 μM.

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Suppliers and manufacturers

Shanghai Standard Technology Co., Ltd.

$0.00/20mg

1,5-Dicaffeoylquinic acid

CAS:19870-46-3
career henan chemical co

$7.00/1KG

CYNARIN

CAS:19870-46-3
TargetMol Chemicals Inc.

$110.00/1mL

1,3-Dicaffeoylquinic acid

CAS:19870-46-3
Henan Tianfu Chemical Co.,Ltd.
Shanghai Zheyan Biotech Co., Ltd.
Chengdu Biopurify Phytochemicals Ltd.
Wuhan ChemNorm Biotech Co.,Ltd.
Hubei Ipure Biology Co., Ltd
Aktin Chemicals, Inc.
HANGZHOU CLAP TECHNOLOGY CO.,LTD

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