CYNARIN

$34 - $4631

Product nameCYNARIN
Cas No19870-46-3
MFC25H24O12
MW516.45
EINECS214-655-7
MDL NumberMFCD13196505

Synonyms

1,3-Dicaffeoylquinic acid;(1S,3R,4R,5R)-1,3-Bis[3-(3,4-dihydroxyphenyl)acryloyloxy]-4,5-dihydroxycyclohexanecarboxylic acid;Dicaffeoylquinic Acid, 1,5-;(1S,3R,4R,5R)-1,3-bis[[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy]-4,5-dihydroxycyclohexane-1-carboxylic acid;Cyclohexanecarboxylic acid, 1,3-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-4,5-dihydroxy-, (1S,3R,4R,5R)-;(1S,3R,4R,5R)-1,3-bis[[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy]-4,5-dihydroxycyclohexane-1-carboxylicaci;19870-46-3 CYNARIN;(1S,3R,4R,5R)-1,3-O-Dicaffeoylquinic acid

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Price

78 prices

Brand less more

aablocks Cayman Chemical Biosynth ChemScene Arctom Biorbyt Ltd AvaChem CSNpharm ApexBio Technology TRC ACHEMBLOCK AK Scientific Synthonix Sigma-Aldrich Crysdot Usbiological American Custom Chemicals Corporation Matrix Scientific
Package less more

100mg 200mg 250mg 500mg 10mm*1mlindmso(solution) 1g 1000mg 1.00g 1mg 5mg 10mg 25mg 20mg 10mm*1mlindmso(solid+solvent) 1mlx10mm(indmso) 50mg

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Brand	Packaging	Price	Product name
aablocks AA00AP1D	5mg	$34	1,3-Dicaffeoylquinic acid
aablocks AA00AP1D	10mg	$53	1,3-Dicaffeoylquinic acid
aablocks AA00AP1D	25mg	$108	1,3-Dicaffeoylquinic acid
aablocks AA00AP1D	50mg	$161	1,3-Dicaffeoylquinic acid
ACHEMBLOCK U106570	50MG	$215	1,5-Dicaffeoylquinic acid
AK Scientific 0210AB	5mg	$284	1,3-O-Dicaffeoylquinicacid
American Custom Chemicals Corporation PXT0003565	5MG	$496.6	1,3-O-DICAFFEOYLQUINIC ACID
ApexBio Technology B8457	10mg	$251	1,3-Dicaffeoylquinic acid
ApexBio Technology B8457	5mg	$157	1,3-Dicaffeoylquinic acid
Arctom SLK-S9512	1mg	$140	1,3-Dicaffeoylquinic acid

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Properties

Boiling point	819.9±65.0 °C(Predicted)
Density	1+-.0.1 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,2-8°C
solubility	soluble5mg/mL, clear, colorless to light yellow
form	Solid
pka	2.50±0.50(Predicted)
color	white to off-white
Stability	Hygroscopic
Major Application	food and beverages
InChIKey	YDDUMTOHNYZQPO-PSEXTPKNSA-N
SMILES	O[C@@H]1C[C@@](C[C@@H](OC(=O)\C=C\c2ccc(O)c(O)c2)[C@@H]1O)(OC(=O)\C=C\c3ccc(O)c(O)c3)C(O)=O

Safety Information

Symbol(GHS)

Signal word

Warning

Hazard statements

H315：Causes skin irritation

H319：Causes serious eye irritation

Precautionary statements

P261：Avoid breathing dust/fume/gas/mist/vapours/spray.

P264：Wash hands thoroughly after handling.

P264：Wash skin thouroughly after handling.

P270：Do not eat, drink or smoke when using this product.

P271：Use only outdoors or in a well-ventilated area.

P280：Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338：IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313：IF SKIN irritation occurs: Get medical advice/attention.

P337+P313：IF eye irritation persists: Get medical advice/attention.

P501：Dispose of contents/container to..…

Description

1,5-Dicaffeoylquinic acid (1,5-DCQA) has been found in A. montana and is an HIV-1 integrase inhibitor and free radical scavenger. 1,5-DCQA inhibits HIV-1 integrase 3'' end processing, end joining, and disintegration with IC₅₀ values of 0.35, 0.56, and 0.84 μg/ml, respectively. It also inhibits HIV-1 replication in MT-2 T lymphoblastoid cells with an ED₅₀value of 2 μg/ml. 1,5-DCQA (0.25-1 μM) reduces the level of free radicals released from human polymorphonuclear (PMN) cells stimulated by N-formyl-Met-Leu-Phe (fMLP; ) in a dose-dependent manner. It also dose-dependently increases cell survival and glutathione (GSH) levels and decreases reactive oxygen species (ROS) production and lactate dehydrogenase (LDH) release in an oxygen-glucose deprivation/reperfusion assay in rat cerebral astrocytes when used at concentrations ranging from 5 to 100 μM.

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Suppliers and manufacturers

Shanghai Standard Technology Co., Ltd.

1,5-Dicaffeoylquinic acid

CAS:19870-46-3
career henan chemical co

$7.00

CYNARIN

CAS:19870-46-3
TargetMol Chemicals Inc.

$110.00

1,3-Dicaffeoylquinic acid

CAS:19870-46-3
Henan Tianfu Chemical Co.,Ltd.
Shanghai Zheyan Biotech Co., Ltd.
Chengdu Biopurify Phytochemicals Ltd.
Wuhan ChemNorm Biotech Co.,Ltd.
Hubei Ipure Biology Co., Ltd
Aktin Chemicals, Inc.
HANGZHOU CLAP TECHNOLOGY CO.,LTD

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