COMBRETASTATIN A-4

$10 - $2880

Product nameCOMBRETASTATIN A-4
Cas No117048-59-6
MFC18H20O5
MW316.35
MDL NumberMFCD03453309

Synonyms

(Z)-2-Methoxy-5-[2-(3,4,5-trimethoxyphenyl)ethenyl]phenol,3,4,5-Trimethoxy-3hydroxy-4methoxy-(Z)-stilbene,CS-A4;Combrestatin A4( 2-Methoxy-5-[2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenol );(Z)-2-Methoxy-5-(3,4,5-trimethoxystyryl)phenol ,98%;2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol;3-[(Z)-2-(3,4,5-Trimethoxyphenyl)ethenyl]-6-methoxyphenol;5-[(Z)-2-(3,4,5-Trimethoxyphenyl)ethenyl]-2-methoxyphenol;Combretastatin A4;(Z)-CombretastatinA4

show less show more

Price

86 prices

Brand less more

TCI Chemical Sigma-Aldrich Cayman Chemical Arctom Crysdot ACHEMBLOCK aablocks TRC Usbiological Biorbyt Ltd ApexBio Technology Matrix Scientific AK Scientific Adipogen Life Sciences Axon Medchem Chem-Impex ChemScene American Custom Chemicals Corporation Biosynth Ambeed DC Chemicals
Package less more

10μg 1mg 5mg 10mg 20mg 25mg 50mg 100mg 100.00mg 250.00mg 250mg 1g 1.00g 10mm*1mlindmso(solid+solvent) 5g 10g 10mm*1mlindmso(solution)

Clear All Done

Brand	Packaging	Price	Product name
aablocks AA000DJW	1mg	$10	Combretastatin A4
aablocks AA000DJW	5mg	$15	Combretastatin A4
aablocks AA000DJW	10mg	$20	Combretastatin A4
aablocks AA000DJW	25mg	$31	Combretastatin A4
aablocks AA000DJW	100mg	$82	Combretastatin A4
aablocks AA000DJW	250mg	$147	Combretastatin A4
aablocks AA000DJW	1g	$381	Combretastatin A4
ACHEMBLOCK R16018	1G	$236	Combretastatin A4
ACHEMBLOCK R16018	100MG	$56	Combretastatin A4
ACHEMBLOCK R16018	5G	$840	Combretastatin A4

1of9

Properties

Melting point	84.5-85.5°C
Boiling point	490.3±45.0 °C(Predicted)
Density	1.184±0.06 g/cm3(Predicted)
storage temp.	-20°C
solubility	DMSO: >10mg/mL
pka	9.65±0.10(Predicted)
form	powder
color	off-white
Merck	14,2494
InChI	InChI=1S/C18H20O5/c1-20-15-8-7-12(9-14(15)19)5-6-13-10-16(21-2)18(23-4)17(11-13)22-3/h5-11,19H,1-4H3/b6-5-
InChIKey	HVXBOLULGPECHP-WAYWQWQTSA-N
SMILES	C1(O)=CC(/C=C\C2=CC(OC)=C(OC)C(OC)=C2)=CC=C1OC

Safety Information

Symbol(GHS)

Signal word

Danger

Hazard statements

H318：Causes serious eye damage

Precautionary statements

P261：Avoid breathing dust/fume/gas/mist/vapours/spray.

P280：Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310：IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P305+P351+P338：IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Combrestatin A4 (CA4) is a potent inhibitor of tubulin polymerization and displays strong inhibitory activity on tumor cell growth. CA4 was shown to impede tumor growth in several cell lines including IMR32 (neuroblastoma), Hs746T (gastric carcinoma), CFPAC-1 (pancreatic carcinoma), and MCF-7 (breast cancer) with IC50 values of 2.16, 5.20, 3.46, and 18.47 nM, respectively. CA4 inhibits tubulin polymerization with an IC₅₀ value of 2.2 μM. Combrestatin A4 is an inhibitor of β Tubulin.

Related product price

168555-66-6 $31-1529 4-Hydroxyphenethyl alcohol $14-840 alpha-Cyperone $46-2200

Suppliers and manufacturers

Shaanxi Dideu Medichem Co. Ltd

$0.10/1KG

COMBRETASTATIN A-4

CAS:117048-59-6
career henan chemical co

$1.00/1KG

COMBRETASTATIN A-4

CAS:117048-59-6
NanJing Spring & Autumn Biological Engineering CO., LTD.

$17.00/20mg

Combretastatin A4 117048-59-6

CAS:117048-59-6
Hebei shuoxi biotechnology co. LTD

$60.00/1KG

Combretastatin A4

CAS:117048-59-6
Nanjing ChemLin Chemical Industry Co., Ltd.
Shanghai Zheyan Biotech Co., Ltd.
Zhejiang ZETian Fine Chemicals Co. LTD
Biochempartner
Chengdu Biopurify Phytochemicals Ltd.
BOC Sciences

More related product prices

168555-66-6
4-Hydroxyphenethyl alcohol
alpha-Cyperone
hydroxygenkwanin
alpha-Terpineol

beta-Sitosterol
Artemether
Hydroxyecdysone
2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one
COMBRETASTATIN A-4

COMBRETASTATIN A1

1of3

Send Inquriy