TNP-ATP (2′,3′-O-(2,4,6-Trinitrophenyl) adenosine 5′-triphosphate) sodium salt has been used :
- To study its blocking effect on neck muscle electromyographic activity stimulated by application of α,β-meATP to the frontal dura.
- To study the effect of blocking purinergic receptors in response to hypercapnia.
- To study the role of P2X4 receptors in BDNF (brain-derived neurotrophic factor) induction in astrocytes.