CB1 RECEPTOR (C-TERM) BLOCKING PEPTIDE

To be used in conjunction with Cayman’s CB1 Receptor (C-Term) polyclonal antibody (Item No. 10006590) to block protein-antibody complex formation during immunochemical analysis of CB1 · The CB1 receptor is a G-protein coupled receptor that binds the active component of cannabis, Δ9-tetrahydrocannabinol.1,2 Human and rat CB1 receptors exhibit 97.3% homology at the amino acid level over the complete protein, and 100% homology within the peptide sequence used to make the Cayman CB1 Receptor polyclonal antibody (Item No. 10006590).3,4 This peptide exhibits no homology with the CB2 receptor. Based on the amino acid sequence, the CB1 receptor has a molecular weight of approximately 52,800.4 The CB1 receptor and the splice variant CB1a are localized mainly in the brain whereas the CB2 receptor is localized predominantly in peripheral tissues, including the spleen and hematopoietic cells.3,4,5,6WARNING This product is not for human or veterinary use.