Brevetoxin PbTx-2, from Karenia brevis (formely known as Ptychodiscus brevis) is a water-soluble polyether neurotoxin that binds to nerve and muscle Na+ channels causing an excessive influx of Na+ across membranes. Binds at site 5 on the voltage-sensitive Na+ channel. Brevetoxin PbTx-2, is an activator of Sodium Channel Protein.
