BIALAPHOS SODIUM SALT;sodium 2-[2-[[2-amino-4-(hydroxy-methyl-phosphoryl)butanoyl]amino]propanoylamino]propanoate;4-[(Hydroxy)(methyl)phosphinyl]-L-Abu-L-Ala-L-Ala-ONa;Meij Herbiace;Meiji Herbiace;MW-801;Sodium salt of L-2-amino-4-(hydroxymethylphosphinoyl)butyryl-L-alanyl-L-alanine;L-Alanine,(2S)-2-amino-4-(hydroxymethylphosphinyl)butanoyl-L-alanyl-, sodium salt (1:1)
P270:Do not eat, drink or smoke when using this product.
P321:Specific treatment (see … on this label).
P405:Store locked up.
Description
Bialaphos is a natural non-selective phytotoxin produced by certain Streptomyces species. It is a pro-toxin, a tripeptide that is converted in vivo to the active agent phosphinothricin, which is a glutamine analog. L-Phosphinothricin inhibits glutamine synthetase (Ki = 6.1 μM), resulting in accumulation of ammonium and disruption of primary metabolism. The bacterial bar gene encodes a phosphinothricin acetyltransferase, which confers resistance to phosphinothricin. Bialaphos is used in the selection of transgenic plants that express the bar gene, usually under the control of a constitutively active viral promoter.