Furafylline is a methyl xanthine derivative with an expanded duration of action than that of theophylline. Furafylline acts as an inhibitor of CYP1A2 (cytochrome p450) and PDE (phosphodiesterase). Inhibition of CYP has the effect of slowing oxidative metabolism of xenobiotics, while inhibition of PDE prevents the hydrolysis of secondary messenger molecules, which in turn prolongs signal transduction and enhances its effects.
