Soluble in DMSO (45 mg/ml); ethanol (10 mg/ml with warming)
form
solid
color
Yellow
Stability
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Safety Information
Symbol(GHS)
Signal word
Warning
Hazard statements
H315:Causes skin irritation
H319:Causes serious eye irritation
H335:May cause respiratory irritation
Precautionary statements
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
Description
AS-8351 is a histone demethylase inhibitor. It has been used in combination with CHIR99021 , A 83-01 , BIX01294 , SC-1 , Y-27632 (Item No. 10005583), OAC2 , SU 16f , and JNJ-10198409 to induce reprogramming of human fetal lung fibroblasts into functional cardiomyocytes.