S(-)-cathinone hydrochloride

Cathinone, the main psychoactive alkaloid from the khat plant (C. edulis), is a potent central stimulant and a naturally occurring analog of amphetamine. Cathinone, the main psychoactive alkaloid from the khat plant (C. edulis), is a potent central stimulant and a naturally occurring analog of amphetamine. (?)-(S)-Cathinone is several times more potent than its (+)-isomer, and its absolute stereochemistry is identical to that of (+)-(S)-amphetamine. Like amphetamine, (?)-(S)-cathinone is a potent releaser of norepinephrine and dopamine from their intracellular stores. With an ED50 value of 0.42 μmol/kg, (?)-(S)-cathinone produces amphetamine-like stimulus effects in rats trained to discriminate 1 mg/kg of (+)-(S)-amphetamine from vehicle. This product is intended for research and forensic applications.