JNK INHIBITOR II, NEGATIVE CONTROL;SAPK INHIBITOR II;N1-METHYL-1,9-PYRAZOLOANTHRONE;N'-METHYL-1,9-PYRAZOLOANTHRONE;SP 600125, negative control;JNK Inhibitor II, Negative Control - CAS 54642-23-8 - Calbiochem;Dibenz[cd,g]indazol-6(2H)-one, 2-methyl-;2-Methyldibenzo[cd,g]indazol-6(2H)-one
SP 600125 is a selective, cell-permeable, reversible inhibitor of JNK isoforms 1-3 with Ki values of 0.19 μM. SP 600125, negative control is a methylated analog of SP 600125 that has much lower affinity for JNK isoforms (IC50s = 18 and 24 μM for JNK2 and JNK3, respectively).