(3R-cis)-1-(6-methoxy-4-quinolyl)-3-(3-vinyl-4-piperidyl)propan-1-one monohydrochloride

$496.44 - $1355

Product name(3R-cis)-1-(6-methoxy-4-quinolyl)-3-(3-vinyl-4-piperidyl)propan-1-one monohydrochloride
Cas No52211-63-9
MFC20H25ClN2O2
MW360.8777
EINECS257-739-9

Synonyms

(3R-cis)-1-(6-methoxy-4-quinolyl)-3-(3-vinyl-4-piperidyl)propan-1-one monohydrochloride ;ViquidilHCl;Viquidilhydrochloride;Quinicine;quinotoxin;Quinotoxine Hydrochloride;(3R,4R)-4-[3-Oxo-3-(6-Methoxyquinolin-4-yl)propyl]-3-vinylpiperidine Hydrochloride;(3R-cis)-3-(3-Ethenyl-4-piperidinyl)-1-(6-Methoxy-4- quinolinyl)-1-propanone Hydrochloride

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Price

2 prices

Brand less more

TRC American Custom Chemicals Corporation
Package less more

5mg 500mg

Clear All Done

Brand	Packaging	Price	Product name
American Custom Chemicals Corporation CCH0039226	5MG	$496.44	QUINICINE HYDROCHLORIDE
TRC Q753500	500mg	$1355	QuinotoxineHydrochloride

Properties

Melting point	184 ±4°
storage temp.	Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility	DMSO (Slightly), Water (Slightly, Sonicated)
form	Solid
color	Pale Yellow to Yellow
Water Solubility	Water: 15 mg/mL (41.57 mM)
Stability	Very Hygroscopic

Safety Information

Symbol(GHS)

Signal word

Warning

Hazard statements

H302：Harmful if swallowed

H312：Harmful in contact with skin

H332：Harmful if inhaled

Precautionary statements

P261：Avoid breathing dust/fume/gas/mist/vapours/spray.

P264：Wash hands thoroughly after handling.

P264：Wash skin thouroughly after handling.

P270：Do not eat, drink or smoke when using this product.

P271：Use only outdoors or in a well-ventilated area.

P280：Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312：IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352：IF ON SKIN: wash with plenty of soap and water.

P304+P340：IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P312：Call a POISON CENTER or doctor/physician if you feel unwell.

P322：Specific measures (see …on this label).

P330：Rinse mouth.

P363：Wash contaminated clothing before reuse.

P501：Dispose of contents/container to..…

Description

Although this alkaloid from the bark of Cinchona species was first isolated by Howard in 1871, it had earlier been prepared by Pasteur by heating the acid sulphate of quinine and Hesse subsequently prepared it in a similar manner from quinidine. The identity of the alkaloid with quinotoxine, formed by heating quinine in H20 or dilute AcOH was proved by von Miller and his co-workers. The base forms a bitter, yellow varnish having [α]_D + 38.6° (CHCI 3 ) and is normally purified through the oxalate nonahydrate which has m.p. 166-7°C;[α]²⁰_D + 24°. The alkaloid yields crystalline salts, the hydrochloride forming colourless leaflets, m.p. l80-2°C; [α]]^13.7_D + 16 26° (H20); the oxime, m.p. l12-6°C; dipicrolonate, m.p. 210°C; the (+)-tropate monohydrate, m.p. l12-3°C or l16-8°C (dry). The p-bromophenylhydrazone forms yellow crystals, m.p. 141°C. Both the N-methyl and N-ethyl derivatives are yellow oils, the former yielding a hydrochloride monohydrate, m.p. l53-5°C; [α]²³_D + 16.6° (H20) and the latter the corresponding hydrochloride, m.p. 202-4°C; [α]²³_D + 68.1 ° (H20). The N-benzoyl derivative crystallizes from C6H6 or MeOH with m.p. l13-4°C; [α]²²_D + 36° (c 2.0, EtOH).
According to de Caro, the minimum lethal dose for white rats is 0.32 gm/kilo compared with 1.25 gm/kilo for quinine and, although it has no anti-malarial action, the alkaloid appears to be less toxic than formerly supposed.

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Suppliers and manufacturers

TargetMol Chemicals Inc.

$39.00/1mg

Viquidil hydrochloride

CAS:52211-63-9
TargetMol Chemicals Inc.

$39.00/1mg

Viquidil hydrochloride

CAS:52211-63-9
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