TRANS-DINOPROSTONE;5-TRANS PROSTAGLANDIN E2;9-OXO-11ALPHA,15S-DIHYDROXY-PROSTA-5E,13E-DIEN-1-OIC ACID;Prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-9-oxo-, (5E,11α,13E,15S)-;Alprostadil EP Impurity H;Prostaglandin Impurity 7;Dinoprostone EP Impurity C;Dinoprostone EP Impurity CQ: What is
Dinoprostone EP Impurity C Q: What is the CAS Number of
Dinoprostone EP Impurity C Q: What is the storage condition of
Dinoprostone EP Impurity C Q: What are the applications of
Dinoprostone EP Impurity C
P308+P313:IF exposed or concerned: Get medical advice/attention.
Description
5-trans PGE2 occurs naturally in some gorgonian corals and is a common impurity in commercial lots of PGE1. It is 18 times more potent than PGE2 in activating adenylate cyclase in NCB-20 cell homogenates. 5-trans PGE2 accelerates fibrinolysis by enhancing plasminogen activation mediated by tissue-type plasminogen activator. It also inhibits platelet aggregation in human PRP with an IC50 of 180 nM.