5,7-dihydroxychromone

$40 - $1452

Product name5,7-dihydroxychromone
Cas No31721-94-5
MFC9H6O4
MW178.14
MDL NumberMFCD14583153

Synonyms

4H-1-Benzopyran-4-one, 5,7-dihydroxy-;5,7-Dihydroxy-4H-1-benzopyran-4-one;5,7-Dihydroxy-γ-chromene-4-one;5,7-Dihydroxy-4-chromone;5,7-Dihydroxychromen-4-one;7-Dihydroxychromone;Arenavirus,5,7 Dihydroxychromone,inhibit,Inhibitor,PARP,Caspase,Keap1-Nrf2,5,7-Dihydroxychromone,5,7Dihydroxychromone,poly ADP ribose polymerase;5,7-Dihydroxychromone-RM

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Price

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Cayman Chemical aablocks Arctom ApexBio Technology ChemScene ACHEMBLOCK AK Scientific Biosynth AvaChem DC Chemicals Sigma-Aldrich Chemenu Crysdot Usbiological American Custom Chemicals Corporation Medical Isotopes, Inc.
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1mg 5mg 10mg 20mg 10mm*1mlindmso(solution) 25mg 10mm(in1mldmso) 50mg 100mg 500mg 1000mg 10mm*1mlindmso(solid+solvent) 1g

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Brand	Packaging	Price	Product name
aablocks AA007ILZ	1mg	$44	5,7-dihydroxychromone
aablocks AA007ILZ	5mg	$99	5,7-dihydroxychromone
aablocks AA007ILZ	10mg	$168	5,7-dihydroxychromone
aablocks AA007ILZ	20mg	$315	5,7-dihydroxychromone
aablocks AA007ILZ	25mg	$356	5,7-dihydroxychromone
aablocks AA007ILZ	50mg	$640	5,7-dihydroxychromone
aablocks AA007ILZ	100mg	$1152	5,7-dihydroxychromone
ACHEMBLOCK W158556	100MG	$580	5,7-dihydroxychromone
ACHEMBLOCK W158556	20MG	$205	5,7-dihydroxychromone
AK Scientific 3455AB	5mg	$229	5,7-Dihydroxychromone

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Properties

Melting point	232-273℃
Boiling point	399℃
Density	1.563
Flash point	171℃
storage temp.	2-8°C
solubility	insoluble in H2O; ≥5.41 mg/mL in EtOH with gentle warming; ≥7.05 mg/mL in DMSO
form	solid
pka	6.57±0.20(Predicted)
color	White to light yellow
Major Application	food and beverages
InChI	1S/C9H6O4/c10-5-3-7(12)9-6(11)1-2-13-8(9)4-5/h1-4,10,12H
InChIKey	NYCXYKOXLNBYID-UHFFFAOYSA-N
SMILES	O1c2c(c(cc(c2)O)O)C(=O)C=C1

Safety Information

Symbol(GHS)

Signal word

Warning

Hazard statements

H315：Causes skin irritation

H319：Causes serious eye irritation

Precautionary statements

P264：Wash hands thoroughly after handling.

P264：Wash skin thouroughly after handling.

P280：Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352：IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338：IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313：IF SKIN irritation occurs: Get medical advice/attention.

P337+P313：IF eye irritation persists: Get medical advice/attention.

Description

5,7-Dihydroxychromone is a flavone decomposition product that has been found in A. hypogaea and has diverse biological activities, including antimicrobial, antioxidant, and neuroprotective properties. It reduces radial growth of the soil pathogenic fungi R. solani and S. rolfsii (IC₅₀s = 18 and 26 μM, respectively) but has no effect on soil pathogenic bacteria of the genus Bradyrhizobium. 5,7-Dihydroxychromone (0.4, 2, and 10 μM) reduces increases in apoptosis and the levels of reactive oxygen species (ROS) induced by 6-OHDA in SH-SY5Y neuroblastoma cells. It also increases the levels of HO-1, NQO1, and GCLc in SH-SY5Y cells when used at concentrations ranging from 0.08 to 10 μM.

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Suppliers and manufacturers

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