P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
Description
C-176 (314054-00-7) is an inhibitor of the signaling molecule STING in mouse cells. It covalently binds to Cys91 of STING preventing activation?via?blockade of palmitoylation at Cys91. Treatment of Trex-/-?mice with C-176 resulted in a significant reduction in serum levels of Type I Interferons and amelioration of systemic inflammation.