(1-Hexyl-1H-indol-3-yl)-1-naphthalenylmethanone

JWH 019 is a cannabimimetic indole that shows a high-affinity for both the central cannabinoid (CB1) and the peripheral cannabinoid (CB2) receptors. The affinities of JWH 019 for both CB1 (Ki = 9.8 nM) and CB2 (Ki = 5.6 nM) are superior to those of the traditional cannabinoid, Δ9-THC (Ki values of 40.7 and 36.4 nM for CB1 and CB2, respectively).