2-AG

$37 - $503.92

Product name2-AG
Cas No53847-30-6
MFC23H38O4
MW378.55
EINECS200-835-2
MDL NumberMFCD01862600

Synonyms

5Z,8Z,11Z,14Z-EICOSATETRAENOIC ACID, 2-GLYCERYL ESTER;(5Z,8Z,11Z,14Z)-5,8,11,14-EICOSATETRAENOIC ACID, 2-HYDROXY-1-(HYDROXYMETHYL)ETHYL ESTER;2-AG;NOLADIN;(5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraenoicacid;2-Hydroxy-1-(hydroxymethyl)ethylester;1,3-dihydroxypropan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate;2-Ara-gl

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Price

7 prices

Brand less more

Sigma-Aldrich Cayman Chemical Tocris American Custom Chemicals Corporation
Package less more

10 1mg 5mg 10mg 25mg

Clear All Done

Brand	Packaging	Price	Product name
American Custom Chemicals Corporation LIP0004988	5MG	$503.92	2-ARACHIDONYL GLYCEROL
Cayman Chemical 62160	25mg	$360	2-Arachidonoyl Glycerol
Cayman Chemical 62160	1mg	$37	2-Arachidonoyl Glycerol
Cayman Chemical 62160	5mg	$135	2-Arachidonoyl Glycerol
Cayman Chemical 62160	10mg	$198	2-Arachidonoyl Glycerol
Sigma-Aldrich A8973	5mg	$398	2-Arachidonyl glycerol
Tocris 1298	10	$207	2-Arachidonyl glycerol

Properties

Boiling point	508.6±50.0 °C(Predicted)
Density	0.992±0.06 g/cm3(Predicted)
Flash point	2 °C
storage temp.	-20°C
solubility	DMSO: 10 mg/ml; Ethanol: Miscible; PBS (pH 7.2): ~150 μg/ml
form	acetonitrile solution
pka	13.54±0.10(Predicted)
color	Colorless to light yellow
CAS DataBase Reference	53847-30-6(CAS DataBase Reference)

Safety Information

Symbol(GHS)

Signal word

Danger

Hazard statements

H225：Highly Flammable liquid and vapour

H319：Causes serious eye irritation

Precautionary statements

P210：Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280：Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312：IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353：IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338：IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

2-Arachidonoyl glycerol (2-AG) is an endogenous agonist of the CB1 and CB2 receptors (Kis = 58 and 145 nM, respectively). Unlike anandamide, 2-AG is present at relatively high levels in the central nervous system; it is the most abundant molecular species of monoacylglycerol found in rat brain. Formation of 2-AG is calcium-dependent and is mediated by the activities of PLC and DAG lipase. 2-AG acts as a full agonist at the CB1 receptor. At a concentration of 0.3 nM, 2-AG induces a rapid, transient increase in intracellular free calcium in NG108-15 neuroblastoma X glioma cells through a CB1 receptor-dependent mechanism. 2-AG is metabolized in vitro by MAG lipase and fatty acid amide hydrolase, with MAG lipase likely being the principle metabolizing enzyme in vivo.

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Suppliers and manufacturers

TargetMol Chemicals Inc.
InvivoChem
Hangzhou MolCore BioPharmatech Co.,Ltd.
GIHI CHEMICALS CO.,LIMITED
Shanghai Acmec Biochemical Technology Co., Ltd.
Mainchem Co., Ltd.
J & K SCIENTIFIC LTD.
3B Pharmachem (Wuhan) International Co.,Ltd.
Ascent Scientific
Chemsky（shanghai）International Co.,Ltd.

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