N-(1-Phenethyl-4-piperidyl)propionanilide hydrochloride

Fentanyl is an agonist of the μ-opioid receptor (Ki = 0.39 nM) that less effectively binds the κ-opioid receptor (Ki = 255 nM) and does not act at the δ-opioid receptor. It is used for anesthesia and chronic pain management. Fentanyl, compared to morphine, is both more effective at reducing pain (ED50 values are 0.0061 vs. 0.33 mg/kg, respectively) and more lethal (LD50 values are 62 vs. 470 mg/kg, respectively). Fentanyl is abused recreationally and is regulated as a Schedule II controlled substance in the United States.

This product is a qualified Reference Material (RM) that has been manufactured and tested to meet ISO17025 and Guide 34 guidelines. These materials are tested using validated analytical methods on qualified instrumentation to ensure traceability of measurements. All traceable RMs may be distinguished by their CofAs and can be downloaded below using the batch number located on the product label. For a representative CofA please contact our technical support.