JWH 200 2'-naphthyl isomer

JWH 200 is a 3-indolyl-1-naphthylmethane that acts as a cannabinoid (CB) receptor agonist, binding to the CB₁ receptor with high affinity (IC₅₀ = 42 nM).¹ This synthetic cannabinoid has been identified as an adulterant of herbal blends.² JWH 200 2’-naphthyl isomer differs structurally from JWH 200 by having the naphthyl group attached at the 2’ position. The biological and toxicological properties of this compound have not been characterized. This product is intended for forensic purposes.