Soluble in DMSO (up to 25 mg/ml) or in Methanol (up to 25 mg/ml).
form
Yellow crystalline solid.
color
White
Stability
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or methanol may be stored at -20°C for up to 3 months.
Description
Niguldipine is a dihydropyridine that acts as a potent, selective α1A-adrenoceptor antagonist (Ki = 0.16 nM). It less potently blocks L- and T-type Ca2+ channels (IC50s = 0.4 and 0.9 μM, respectively).
