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ChemicalBook >> CAS DataBase List >>Rapamycin

Rapamycin suppliers

Rapamycin

CAS:: 53123-88-9

MF:: C51H79NO13

MW:: 914.17

SecurityInformation

Symbol(GHS) ：: GHS08

Signal word ：: Warning

Hazard statements ：: H351-H361fd

Precautionary statements ：: P201-P202-P280-P308+P313-P405-P501

Hazard Codes ：: Xi,Xn,F

Risk Statements ：: 36/38-36-20/21/22-11

Safety Statements ：: 22-24/25-37/39-26-36/37-16

RIDADR ：: UN 1648 3 / PGII

WGK Germany ：: 2

RTECS ：: VE6250000

Autoignition Temperature：: 301 °C

HS Code ：: 29349990

Hazardous Substances Data：: 53123-88-9(Hazardous Substances Data)

Toxicity：: LD50 in mice (mg/kg): 600 i.p.; >2,500 orally (Vézina)

Use：: Rapamycin is a triene macrolide discovered in 1974 as a metabolite of Streptomyces hygroscopicus found in a soil obtained on Rapa Nui (Easter Island). Rapamycin displayed potent and selective antifungal activity, notably against Candida albicans. Interest in the metabolite waned until the structural relationship to the potent immunosuppressant fujimycin (Antibiotic FK506) was recognised in the mid-1980s. This recognition led to the re-discovery of rapamycin as a highly selective antitumor and immunosuppressant. Rapamycin inhibits the activity of the protein, mTOR (mammalian target of rapamycin) which functions in a signalling pathway to promote tumor growth. Rapamycin binds to a receptor protein (FKBP12). The rapamycin/FKB12 complex then binds to mTOR and prevents interaction of mTOR with target proteins in this signalling pathway.

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You can find Rapamycin suppliers, manufacturers, and distributors from countries such as China, United States and the India here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.

Seasons Biotechnology Co., Ltd.

Rapamycin
Remarks: Purity: 98% | Package: Gram to Kilogram Class
CHINA Trader

Guangzhou Tengyue Chemical Co., Ltd.

Rapamycin
Remarks: Purity: 99% purity,WhatsApp+86 18102676775 | Package: 10g;230USD
TEL: 86-18148706580
CHINA Trader

￥540.00/10g

BOC Sciences

Rapamycin (Sirolimus)
Remarks: Purity: >98% | CustNote: BOC Sciences also provides custom synthesis services for Rapamycin (Sirolimus).
TEL: 16314854226
UNITED STATES Reagent