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ChemicalBook >> CAS DataBase List >>1-Adamantanol

1-Adamantanol suppliers

1-Adamantanol

CAS:: 768-95-6

MF:: C10H16O

MW:: 152.23

SecurityInformation

Symbol(GHS) ：: GHS07

Signal word ：: Warning

Hazard statements ：: H315-H319-H335

Precautionary statements ：: P261-P271-P280

Hazard Codes ：: Xi

Risk Statements ：: 36/37/38

Safety Statements ：: 22-24/25-36-26

WGK Germany ：: 3

RTECS ：: AU4980000

Hazard Note ：: Irritant

HS Code ：: 29061900

Use：: 1-adamantanol is also known as 1-hydroxide adamantane, 1-tricyclo [3.3.1.1 (3.7)] decyl alcohol. At room temperature, it is white crystalline powder with the melting point higher than 240 ℃. It is soluble in organic solvents and insoluble in water with sublimation property. It can be used for the manufacture of synthetic adamantane derivatives and adapalene. It can react with vinylidene chloride to generate 1-adamantane acetic acid. 1-adamantyl acetate can further undergo bromination and hydrolyzed into 3-hydroxy-1-adamantyl acetate which can further react with vinylidene chloride to give 1, 3-adamantane di-acetic acid. 1-adamantanol can have Friedel-Crafts alkylation reaction acetanilide in the 98% sulfuric acid medium at room temperature for direct synthesis of 1, 3-bis (4-acetylamino-phenyl) adamantane which can undergo alkaline hydrolysis for synthesis of 1, 3 bis (4-aniline) adamantane. The synthetic route has many advantages including relative high reaction yield and easy purification, etc., therefore greatly facilitating the synthesis of 1, 3-diaryl adamantane derivatives. The above information is edited by the Chemicalbook of Dai Xiongfeng.

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Huzhou Chenxi Environmental Protection Technology Co. , Ltd.