디메트모르프

한글명:디메트모르프

카스 번호110488-70-5

상품명:Dimethomorph

CBNumberCB9774944

분자식C21H22ClNO4

포뮬러 무게387.86

MOL 파일110488-70-5.mol

동의어(한글)

4-(3-(4-클로로페닐)-3-(3,4-디메톡시페닐)아크릴로일)몰폴린

디메트모르프

4-(3-(4-클로로페닐)-3-(3,4-디메톡시페닐)아크릴로일)몰폴린(4-(3-(4-CHLOROPHENYL)...

화학적 성질

녹는점	125-149°C
끓는 점	584.9±50.0 °C(Predicted)
밀도	1.231±0.06 g/cm3(Predicted)
증기압	1 x 10^-6 Pa (25 °C)
저장 조건	Sealed in dry,Room Temperature
용해도	Chloroform: Soluble,Methanol: Soluble
산도 계수 (pKa)	-1.19±0.20(Predicted)
수용성	50mg l^-1(20-23°C)
물리적 상태	Solid
색상	White to off-white
Merck	13,3248
BRN	8794474
LogP	2.680
EPA	Dimethomorph (110488-70-5)

위험 및 안전 성명

위험품 표기	N
위험 카페고리 넘버	51/53
안전지침서	61
유엔번호(UN No.)	UN3077 9/PG 3
WGK 독일	2
RTECS 번호	QE0478300
유해 물질 데이터	110488-70-5(Hazardous Substances Data)
독성	LD50 in rats (mg/kg): 321 i.p.; 3900 orally; >5000 dermally; LC50 (4-hr inhalation): >4.2 mg/ml (Veenstra, Owen)

그림문자(GHS)

디메트모르프 MSDS

디메트모르프 화학적 특성, 용도, 생산

개요
Dimethomorph is a morpholine fungicide that inhibits fungal cell wall formation. It inhibits mycelial growth of the oomycete fungi P. citrophthora, P. parasitica, P. capsici, and P. infestans (EC₅₀s = 0.14, 0.38, <0.1, and 0.16-0.3 μg/ml, respectively) but is less active against the green algae species C. vulgaris or S. obliquus in vitro (EC₅₀s = 47.46 and 44.87 μg/ml, respectively). It inhibits androgen receptor (AR) activity in a reporter assay in MDA-kb2 human breast cancer cells but not in a yeast antiandrogen screen (IC₂₀s = 0.263 and 38.5 μM, respectively). It is not toxic to rats (LD₅₀ = 3,900 mg/kg) or goldfish (C. auratus; LC₅₀ = >32 μg/ml).
화학적 성질
Off-White Solid
용도
Dimethomorph is a systemic fungicide which exhibits protectant, curative and antisporulant activities. It is active against fungal diseases such as leaf blight, downy mildew, damping off and foot-rot caused by Phytophthora spp. in/on grapes, potatoes and tomatoes.
정의
ChEBI: A mixture of (E)- and (Z)-dimethomorph in an unspecified ratio. It is used as a systemic fungicide used on vines, potatoes, and greenhouse crops; only the Z isomer has fungicidal activity.
농업용
Fungicide: A systemic fungicide that protects crops from mold. It also kills mold and prevents their spread; controls late blight on tomatoes; and is used as a wood preservative to control downey mildew.
상품명
ACROBAT® WP; FORUM DC®, [manco- zeb + dimethomorph]; CME 151®; STATURE®
신진 대사 경로
Limited data are available in the open literature. Information presented in this summary is abstracted from the data evaluation published by the Pesticide Safety Directorate (PSD, 1994). Dimethomorph is a (1:l) mixture of the E- and Z-isomers. The Z-isomer has been shown to have all the intrinsic biological activities. The isomerisation of the E- and Z-isomers was observed when resolved isomers were exposed to UV light. Dimethomorph undergoes extensive degradation and metabolism in soil, plants and animals. The major metabolic pathway is the O-demethylation of one of the phenolic methoxy moieties to the corresponding phenols and conjugates. Other metabolic reactions include the oxidation of one of the CH2 moieties of the morpholine ring and the cleavage/opening of the morpholine ring (Scheme 1).

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