Nisoxetine

Nisoxetine 화학적 특성, 용도, 생산

• 용도

  Antidepressant.

• 일반 설명

  Nisoxetine is a SNERI and is an antidepressant. Most activityresides in the β-isomer.

• Clinical Use

  Nisoxetine was the initial phenoxyphenylpropylamine synthesized in the Lilly research laboratories during the early 1970s from the rearrangement of an oxygen atom in diphenyhydramine, a diphenylmethoxyethylamine, to a phenoxyphenylpropylamine. Nisoxetine was discovered to be a potent and very selective SNRI, with little affinity for other receptors. It underwent clinical studies as an alternative to Lilly's best-selling antidepressant, nortriptyline, but without the adverse effects associated with the tricyclic secondary amines. It was never marketed, however, because of a greater interest in developing its 4-trifluoromethyl analogue, fluoxetine, an SSRI.

Nisoxetine 준비 용품 및 원자재

Nisoxetine 공급 업체

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