2'-Deoxycytidine

한글명:2'-Deoxycytidine

카스 번호951-77-9

상품명:2'-Deoxycytidine

CBNumberCB7452978

분자식C9H13N3O4

포뮬러 무게227.22

MOL 파일951-77-9.mol

화학적 성질

녹는점	209-211 °C(lit.)
끓는 점	368.93°C (rough estimate)
밀도	1.3171 (rough estimate)
굴절률	59 ° (C=1, H2O)
저장 조건	-20°C
용해도	H₂O: 50 mg/mL, 투명, 무색
물리적 상태	결정성 분말
산도 계수 (pKa)	14.03±0.60(Predicted)
색상	하얀색
수용성	물에 불용성, DMSO.
BRN	87567
InChI	InChI=1S/C9H13N3O4/c10-7-1-2-12(9(15)11-7)8-3-5(14)6(4-13)16-8/h1-2,5-6,8,13-14H,3-4H2,(H2,10,11,15)/t5-,6+,8+/m0/s1
InChIKey	CKTSBUTUHBMZGZ-SHYZEUOFSA-N
SMILES	OC[C@H]1O[C@@H](N2C=CC(N)=NC2=O)C[C@@H]1O
CAS 데이터베이스	951-77-9(CAS DataBase Reference)
NIST	Deoxycytidine(951-77-9)
EPA	Cytidine, 2'-deoxy- (951-77-9)

위험 및 안전 성명

안전지침서

24/25

WGK 독일

RTECS 번호

HA3800000

F 고인화성물질

TSCA

Yes

HS 번호

29349990

NFPA 704:

	0
1		0

그림문자(GHS)

2'-Deoxycytidine MSDS

2'-Deoxycytidine 화학적 특성, 용도, 생산

화학적 성질
White crystalline powder
용도
A deoxyribonucleoside
정의
ChEBI: A pyrimidine 2'-deoxyribonucleoside having cytosine as the nucleobase.
일반 설명
2′-Deoxycytidine (deoxyC) is one of the deoxynucleosides containing cytosine as the nucleobase. It is found in the blood, feces, and urine.
Safety Profile
Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
Purification Methods
Purify 2'-deoxycytidine by recrystallisation from MeOH/Et2O or EtOH and dry it in air. [NMR: Miles J Am Chem Soc 85 1007 1963, UV: Fox & Shugar Biochim Biophys Acta 9 369 1952.] The hydrochloride crystallises from H2O/EtOH and has m 174o(dec, 169-173o). [Walker & Butler Can J Chem 34 1168 1956.] The picrate has m 208o(dec). [Fox et al. J Am Chem Soc 83 4066 1961, Beilstein 25 III/IV 3662.]
Structure and conformation
2'-Deoxycytidine monohydrate (dCMP) is a nucleoside phosphate in being comprised of a deoxyribonucleoside and one phosphate group. It has a deoxyribose as its sugar constituent with one phosphate group attached. Its nucleoside contains a pyrimidine base, i.e., a cytosine attached to the deoxyribose sugar. It has only one phosphate group attached to the nucleoside. Its conjugate acid form is deoxycytidylic acid, whereas its conjugate base form is deoxycytidylate. dCMP, instead of having a hydroxyl group on the 2′ carbon of the sugar component as it is in Cytidine monophosphate (CMP), has it reduced to a hydrogen atom (thus, deoxy- in its name). dCMP is one of the monomeric units that constitute DNA, whereas CMP is one of the monomeric units that make up RNA.

2'-Deoxycytidine 준비 용품 및 원자재

2'-Deoxycytidine 공급 업체

2'-Deoxycytidine 관련 검색

Send Inquriy