규산 알루미늄 마그네슘

그림문자(GHS)

• 그림문자(GHS)

  

• 신호 어

  Warning

• 유해·위험 문구

  H351：암을 일으킬 것으로 의심됨 (노출되어도 암을 일으키지 않는다는 결정적인 증거가 있는 노출경로가 있다면 노출경로 기재)

• 예방조치문구

  P201：사용 전 취급 설명서를 확보하시오.

  P202：모든 안전 조치 문구를 읽고 이해하기 전에는 취급하지 마시오.

  P281：요구되는 개인 보호구를 착용하시오

  P308+P313：노출 또는 접촉이 우려되면 의학적인 조치· 조언를 구하시오.

  P405：밀봉하여 저장하시오.

  P501：...에 내용물 / 용기를 폐기 하시오.

규산 알루미늄 마그네슘 화학적 특성, 용도, 생산

• 화학적 성질

  Attapulgite occurs as a light cream colored, very fine powder. Particle size ranges depend on the grade and manufacturer.

• 용도

  Worldwide attapulgite production in 1983 was estimated at about 1.1 million tons, of which 84% came from the United States. The primary use of attapulgite is as an animal waste absorbent (cat litter). Other important uses of attapulgite in the United States are as a component of drilling muds, as oil and grease absorbents, and in fertilizer and pesticide formulations.

• 생산 방법

  Attapulgite occurs naturally as the mineral palygorskite.

• 정의

  A hydrated aluminum-magnesium silicate, the chief ingredient of fuller’s earth.

• 위험도

  Possible carcinogen.

• Pharmaceutical Applications

  Attapulgite is widely used as an adsorbent in solid dosage forms. Colloidal clays (such as attapulgite) absorb considerable amounts of water to form gels and in concentrations of 2–5% w/v usually form oil-in-water emulsions. Activated attapulgite, which is attapulgite that has been carefully heated to increase its absorptive capacity, is used therapeutically as an adjunct in the management of diarrhea.

• Safety Profile

  Suspected carcinogen with experimental neoplastigenic and tumorigenic data. When heated to decomposition it emits acrid smoke and irritating fumes.

• Safety

  Attapulgite is widely used in pharmaceutical formulations and is generally regarded as an essentially nontoxic and nonirritant material. It is not absorbed following oral administration. In oral preparations, activated attapulgite up to 9 g is used in daily divided doses as an adjunct in the management of diarrhea.

• 저장

  Attapulgite can adsorb water. It should be stored in an airtight container in a cool, dry, location.

• 비 호환성

  Attapulgite may decrease the bioavailability of some drugs such as loperamide and riboflavin. Oxidation of hydrocortisone is increased in the presence of attapulgite.

• Regulatory Status

  Included in nonparenteral medicines licensed in a number of countries worldwide including the UK and USA.

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