옥시코나졸

옥시코나졸 화학적 특성, 용도, 생산

• 용도

  Antifungal.
  Oxiconazole (Oxistat) is a synthetic imidazole that works, in part, by inhibiting ergosterol 2,3-epoxidase synthesis and thereby disrupting cell membrane integrity.

• 정의

  ChEBI: An oxime O-ether that is the 2,4-dichlorobenzyl ether of the oxime obtained by formal condensation of hydroxylamine with the carbonyl group of acetopnenone in which the phenyl group is substituted by chlorines at positions 2 and 4, and i which one of the hydrogens of the methyl group is replaced by a 1H-imidazol-1-yl group. An antifungal agent, it is used (generally as the nitrate salt) in creams and powders for the topical treatment of fungal skin infections.

• Indications

  Topical treatment of mycoses of the skin induced or sustained by fungi such as dermatophytes and yeasts. In addition, oxiconazole is indicated for therapy of vulvovaginal mycoses caused by Candida species and Candida (Torulopsis) glabrata.

• Antimicrobial activity

  Broad-specktrum imidazole antimycotic with activity against almost all species of pathogenic fungi.

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