헥사미딘다이이세티오네이트

한글명:헥사미딘다이이세티오네이트

카스 번호659-40-5

상품명:Hexamidine diisethionate

CBNumberCB5901139

분자식C22H32N4O6S

포뮬러 무게480.58

MOL 파일659-40-5.mol

동의어(한글)

헥사미딘다이이세티오네이트

화학적 성질

녹는점	246-247° (dec)
밀도	671[at 20℃]
증기압	0Pa at 20℃
용해도	물에 조금 녹고, 에탄올(96%)에 약간 녹고, 염화메틸렌에는 거의 녹지 않습니다.
수용성	48.2g/L at 20℃
InChIKey	NBVZMBLJRHUOJR-UHFFFAOYSA-N
SMILES	C(CO)S(O)(=O)=O.O(C1C=CC(C(N)=N)=CC=1)CCCCCCOC1C=CC(C(N)=N)=CC=1
LogP	4.47 at 25℃

위험 및 안전 성명

유엔번호(UN No.)	2811
WGK 독일	3
위험 등급	6.1(b)
포장분류	III

그림문자(GHS)

헥사미딘다이이세티오네이트 화학적 특성, 용도, 생산

화학적 성질
White or slightly yellow powder, hygroscopic
용도
hexamidine diisethionate is an anti-microbial and preservative targeting fungi and yeast. It may also have some emollient capacities.
색상 색인 번호
Hexamidine is an antiseptic active against Grampositive bacteria and fungi, used as a disinfectant and a preservative in cosmetics. It induces papulo-vesicular and diffuse allergic contact dermatitis.
Toxicology
Acute oral LD(50) values of Hexamidine Diisethionate were 0.71 to 2.5 g/kg in mice and 0.75 g/kg in rats. Dermal exposure to 4 g/kg Hexamidine Diisethionate in rats or up to 9.4 ml/kg of a 0.1% Hexamidine Diisethionate solution under occlusion in rabbits produced no mortality or other signs of toxicity. The no-observed-effect level (NOEL) for oral subchronic toxicity of Hexamidine Diisethionate in rats was 50 mg/kg/day. No signs of toxicity were observed with 2% Hexamidine Diisethionate in subchronic studies using rabbits. Application of 0.1 ml of 0.11% Hexamidine Diisethionate in aqueous solution to the eyes of rabbits produced transient reactions; 0.05% produced no reactions. Slight erythema was observed with 0.10% Hexamidine Diisethionate applied to the abraded skin of 1/11 albino rabbits. A 40% solution of Hexamidine Diisethionate applied to 10% of the body surface of rats produced slight erythema, slight edema, and scabbing in some animals at varying times after treatment. Hexamidine Diisethionate was not a sensitizer in the guinea pig maximization test or in an intracutaneous guinea pig sensitization test. Hexamidine Diisethionate was not a photosensitizer in albino rabbits. Hexamidine Diisethionate was not mutagenic in a bacterial reverse mutagenicity assay or clastogenic in mammalian cells. Hexamidine Diisethionate at 0.10% did not provoke primary irritation, inflammation, or sensitization in a clinical test of 200 human subjects^[1].

헥사미딘다이이세티오네이트 공급 업체

헥사미딘다이이세티오네이트 관련 검색

Send Inquriy