다클라타스비르

그림문자(GHS)

• 그림문자(GHS)

  

• 신호 어

  Warning

• 유해·위험 문구

  H302：삼키면 유해함

• 예방조치문구

  P264：취급 후에는 손을 철저히 씻으시오.

  P264：취급 후에는 손을 철저히 씻으시오.

  P270：이 제품을 사용할 때에는 먹거나, 마시거나 흡연하지 마시오.

  P301+P312：삼켜서 불편함을 느끼면 의료기관(의사)의 진찰을 받으시오.

  P330：입을 씻어내시오.

  P501：...에 내용물 / 용기를 폐기 하시오.

다클라타스비르 화학적 특성, 용도, 생산

• 용도

  Daclatasvir, inhibits the HCV protein NS5A, and thus can be used as a drug candidate for the treatment of hepatitis C (HCV).

• 정의

  ChEBI: Daclatasvir is a member of the class of biphenyls that is a potent inhibitor of nonstructural protein 5A and is used (as its hydrochloride salt) for treatment of hepatitis C. It has a role as a nonstructural protein 5A inhibitor and an antiviral drug. It is a member of biphenyls, a member of imidazoles, a carbamate ester, a carboxamide and a valine derivative. It is a conjugate base of a daclatasvir(2+).

• Mechanism of action

  Daclatasvir is an inhibitor of NS5A, a phosphoprotein that plays an important role in hepatitis C replication.Daclatasvir reduces serum HCV RNA levels. It disrupts HCV replication by inhibiting viral RNA replication and viral assembly and by inhibiting phosphorylation of NS4A, thereby inhibiting the formation and activation of the HCV replication complex.

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