Alkofanone

Alkofanone 화학적 특성, 용도, 생산

• Originator

  Clafanone ,Roche ,US ,1956

• Manufacturing Process

  38 g benzal-acetophenone and 25 g p-aminobenzene-sulfinic acid are refluxed for 5 hours in 700 cc of 85% ethyl alcohol. Fine crystals soon begin to appear and fill the reaction vessel. While still hot, the mixture is suction-filtered. The reaction product is washed first with 750 cc warm absolute alcohol, then with 500 cc water, and finally again with 300 cc alcohol, and then dried in vacuum. Yield 32 g. MP 210-212°C with decomposition.

• Therapeutic Function

  Antidiarrheal

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