2-Bromo-5-chloro-1,3-difluorobenzene

그림문자(GHS)

• 그림문자(GHS)

  

• 신호 어

  Warning

• 유해·위험 문구

  H302：삼키면 유해함

  H315：피부에 자극을 일으킴

  H319：눈에 심한 자극을 일으킴

  H335：호흡 자극성을 일으킬 수 있음

• 예방조치문구

  P261：분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.

  P305+P351+P338：눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.

2-Bromo-5-chloro-1,3-difluorobenzene 화학적 특성, 용도, 생산

• Synthesis

  2-Bromo-5-chloro-1,3-difluorobenzene is synthesised using 4-bromo-3,5-difluoroaniline as a raw material by chemical reaction. The specific synthesis steps are as follows:
  4-bromo-3,5-difluoroaniline (25.0g, 117mmol), copper chloride (I) (23.1g, 230mmol) and copper chloride (II) (47.0g, 350mmol) in acetonitrile (150 mL) mixed solution in, it was added dropwise acetonitrile (50 mL) solution of isoamyl nitrite (49.0mL, 350mmol) at room temperature. After stirring for 4 hours at room temperature the mixture solution, poured into 2N hydrochloric acid (300mL), diethyl - ether (200m And extracted with L × 3). The organic layer was washed with saturated brine, dried over anhydrous magnesium sulfate, and the solvent was evaporated under reduced pressure to obtain a crude product of a brown solid. By purifying this product by a silica gel column (hexane), 2-bromo-5-chloro-1,3-difluorobenzene as a yellow oil (21.4 g, yield: 81%) was obtained.
  

2-Bromo-5-chloro-1,3-difluorobenzene 준비 용품 및 원자재

2-Bromo-5-chloro-1,3-difluorobenzene 공급 업체

Global(104)Suppliers

2-Bromo-5-chloro-1,3-difluorobenzene 관련 검색