H-GLY-PRO-ARG-PRO-NH2

H-GLY-PRO-ARG-PRO-NH2 화학적 특성, 용도, 생산

• 용도

  Gly-Pro-Arg-Pro amide has been used-
  
  • as a constituent of buffer during fluid-phase and bound thrombin inhibition assays, to determine the activity of thrombin
  • for blocking fibrin polymerization and preventing fibrin clot formation in presence of α-thrombin, in blood obtained from mice
  • during preparation of human soluble fibrin, to block the polymerization of soluble fibrin

• 일반 설명

  Gly-Pro-Arg-Pro is a peptide that mimics the N-terminal Gly-Pro-Arg region in the a chain of fibrin protein.

• Biochem/physiol Actions

  Gly-Pro-Arg-Pro peptide suppresses the early steps of fibrin polymerization. The amide derivative of this peptide prevents the degradation of fibrinogen and fragment D by plasmin, even in the presence of EGTA (ethylene glycol-bis(β-aminoethyl ether)-N,N,N′,N′-tetraacetic acid).

H-GLY-PRO-ARG-PRO-NH2 공급 업체

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