임프로술판

임프로술판 화학적 특성, 용도, 생산

• Originator

  Protecton,Yoshitomi,Japan,1980

• Manufacturing Process

  A solution of 5 g of bis(3-methylsulfonyloxypropyl)amine hydrochloride in 20 ml of ice water is neutralized with 1N sodium carbonate solution. The resulting amine base is extracted with five 20 ml portions of chloroform. The combined extract is dried over anhydrous sodium sulfate, the solvent is distilled off under reduced pressure, and the residue is dissolved in 20 ml of ethanol. To the ethanol solution is added slowly with stirring under ice cooling a solution of 2.6 g of p-toluenesulfonic acid in 30 ml of ethanol. The white precipitate formed is collected by filtration and recrystallized from ethanol to give 5.0 g of white crystalline bis(3-methylsulfonyloxypropyl)amine p-toluenesulfonate melting at 115°C to 116°C.

• Therapeutic Function

  Antitumor

임프로술판 준비 용품 및 원자재

임프로술판 공급 업체

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