1-Dibenzofuranylboronic Acid

그림문자(GHS)

• 그림문자(GHS)

  

• 신호 어

  Warning

• 유해·위험 문구

  H302：삼키면 유해함

  H315：피부에 자극을 일으킴

  H319：눈에 심한 자극을 일으킴

  H335：호흡 자극성을 일으킬 수 있음

• 예방조치문구

  P261：분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.

  P305+P351+P338：눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.

1-Dibenzofuranylboronic Acid 화학적 특성, 용도, 생산

• 용도

  Dibenzo[b,d]furan-1-ylboronic acid can be used as an intermediate in organic synthesis, mainly used in laboratory research and development and chemical production processes.

• Synthesis

  
  180 g (728 mmol) of 1-bromodibenzofuran aredissolved in 1500 ml of dry THF and cooled to -78?? C. 305 ml (764 mmol/2.5 M in hexane) of n-butyllithium are added at this temperature over the course of about 5 min., and the mixture is subsequently stirred at -78?? C. for a further 2.5 h. 151 g (1456 mmol) of trimethyl borate are added as rapidly as possible at this temperature, and the reaction mixture is allowed to come slowly to room temperature (about 18 h). The reaction solution is washed with water, and the precipitated solid and the organic phase are dried azeo- tropically with toluene. The crude product is washed by stirring with toluene/methylene chloride at about 40?? C. and filtered off with suction. Yield: 146 g (690 mmol), 95% of theory.

1-Dibenzofuranylboronic Acid 공급 업체

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