Angiotensin acetate

Angiotensin acetate 화학적 특성, 용도, 생산

• 용도

  [Asn¹, Val⁵]-Angiotensin II has been used:
  
  • to study the effects of ACTH, serotonin, Ang II, carbachol and elevated [K⁺] on catecholamine and serotonin release
  • to induce cyclophilin D (CypD)–dependent mitochondrial vascular superoxide (O2^{. -} ) production in hypertension
  • to increase the homocysteine-induced ER stress-inducible, ubiquitin-like domain member 1 (HERPUD1) protein level in HeLa cells
  
  

• 일반 설명

  Angiotensin II is a renin-angiotensin system (RAS) effector molecule, which binds to angiotensin II type-1 (AT₁R) and angiotensin II type-2 (AT₂R) receptors. The gene is located on human chromosome 3q24. Angiotensin II is mainly expressed in vessel walls, lung and kidney.

• Biochem/physiol Actions

  Synthetic angiotensin agonist that is involved in the regulation of blood pressure, water consumption, and hydromineral balance in fish.

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