카파미놀

카파미놀 화학적 특성, 용도, 생산

• Originator

  Rhinoptil,Promonta,W. Germany,1974

• Manufacturing Process

  21 g 8-chlorocaffeine and 15 g beta-N-methylaminoethanol are heated to 140°-160°C for 30 minutes. Then the temperature is increased for 15-20 minutes to 165°-170°C. On cooling a colorless mass of crystals results. This is boiled with 50-60 ml ethanol and crystallized. Colorless crystals result which are soluble in water up to about 6%; pH of the aqueous solution is 6.9. The yield is 19 g while the MP is 162°-164°C.

• Therapeutic Function

  Nasal decongestant

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