7-이소프로폭시-3-페닐-4H-1-벤조피란-4-원

한글명:7-이소프로폭시-3-페닐-4H-1-벤조피란-4-원

카스 번호35212-22-7

상품명:Ipriflavone

CBNumberCB0698496

분자식C18H16O3

포뮬러 무게280.32

MOL 파일35212-22-7.mol

동의어(한글)

7-이소프로폭시-3-페닐-4H-1-벤조피란-4-원

화학적 성질

녹는점	116-120 °C(lit.)
끓는 점	363.04°C (rough estimate)
밀도	1.2170 (rough estimate)
굴절률	1.4700 (estimate)
저장 조건	Sealed in dry,Room Temperature
용해도	DMF:20.0(Max Conc. mg/mL);71.35(Max Conc. mM) DMF:PBS (pH 7.2) (1:4):0.2(Max Conc. mg/mL);0.71(Max Conc. mM) DMSO:33.11(Max Conc. mg/mL);118.11(Max Conc. mM) Ethanol:1.5(Max Conc. mg/mL);5.35(Max Conc. mM)
물리적 상태	powder to crystal
색상	흰색에서 거의 흰색
Merck	14,5074
InChI	InChI=1S/C18H16O3/c1-12(2)21-14-8-9-15-17(10-14)20-11-16(18(15)19)13-6-4-3-5-7-13/h3-12H,1-2H3
InChIKey	SFBODOKJTYAUCM-UHFFFAOYSA-N
SMILES	C1OC2=CC(OC(C)C)=CC=C2C(=O)C=1C1=CC=CC=C1
LogP	4.245 (est)
CAS 데이터베이스	35212-22-7(CAS DataBase Reference)

위험 및 안전 성명

위험품 표기	Xi
위험 카페고리 넘버	36/37/38
안전지침서	24/25-36/37/39-27-26
WGK 독일	2
RTECS 번호	DJ3100500
HS 번호	29329990

그림문자(GHS)

7-이소프로폭시-3-페닐-4H-1-벤조피란-4-원 MSDS

7-이소프로폭시-3-페닐-4H-1-벤조피란-4-원 화학적 특성, 용도, 생산

개요
Ipriflavone, a derivative of isoflavone, is a calcium metabolism regulator useful in the treatment of primary and secondary osteoporosis, as well as disorders of osteogenesis. It appears to be without significant side-effects.
화학적 성질
white powder
용도
7-Isopropoxy-3-phenyl-4H-1-benzopyran-4-one (Ipriflavone) has been used as a model drug in a study to functionalize the mesoporous bioactive glasses (MBG). Study suggested that since ipriflavone is a hydrophobic anti-osteoporotic drug, it easily attaches to the surface of MBG and results in long-term drug delivery.
정의
ChEBI: Ipriflavone is a member of the class of isoflavones that is isoflavone in which the hydrogen at position 7 is replaced by an isopropoxy group. A synthetic isoflavone, it was formerly used for the treatment of osteoporosis, although a randomised controlled study failed to show any benefit. It is still used to prevent osteoporosis in post-menopausal women. It has a role as a bone density conservation agent. It is a member of isoflavones and an aromatic ether.
benefits
Ipriflavone is used clinically to treat osteoporosis. Bodybuilders also use ipriflavone, but enough experimental data supports this purpose. It has been shown to have anti-inflammatory and antioxidant activity. It helps to reduce bone loss, increase bone density, and reduce the risk of developing osteoporosis. It has also been found to help reduce neuroinflammation . In addition, it has been found to help reduce the risk of certain types of cancer, improve cognitive function and reduce the risk of depression.
일반 설명
7-Isopropoxy-3-phenyl-4H-1-benzopyran-4-one (Ipriflavone), a synthetic flavonoid, is reported to stimulate the activity of osteoblasts. It is reported to promote the deposition of calcium and the formation of mineralized nodules by newborn rat calvarial osteoblast-like (ROB) cells as well as the activity of alkaline phosphatase. Ipriflavone, an isoflavone derivative, is a new drug used to decrease bone loss in osteoporosis.
부작용
Ipriflavone should be taken under medical supervision only. It can produce side effects such as stomach pain, diarrhoea, dizziness, etc. It may have a sudden increase in the WBC count if administered for six months or more. When the treatment with Ipriflavone is on, it is suggested that the WBC count should be monitored.

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