アセジアスルホンナトリウム

アセジアスルホンナトリウム 化学特性,用途語,生産方法

• 効能

  抗菌薬, 抗マラリア薬

• Originator

  Solfone ,Bracco

• Manufacturing Process

  24.8 g of 4,4'-diaminodiphenyl sulfone, 150 g of methyl chloroacetate and 150 ml of ethanol are refluxed together and refluxed for 24 hours. The alcohol and excess methyl chloroacetate are then distilled off on a steam bath under reduced pressure. The residue consisting of the hydrochloride salt of 4-amino- 4'-(carbomethoxymethylamino)diphenyl sulfone is mixed with of alcoholic solution containing 2.5 g lithium hydroxide and refluxed for 4 hours on the steam bath. Most of the alcohol is removed by distillation and the residual lithium salt of 4-amino-4'-(carboxymethylamino)diphenyl sulfone taken up water. The solution is filtered and dilute HCl added until no more separation occurs. The 4-amino-4'-(carboxymethylamino)diphenyl sulfone thus obtained is collected and dried.
  The sodium salt of 4-amino-4'-(carboxymethylamino)diphenyl sulfone is prepared by dissolving the free acid in an aqueous solution containing one equivalent of sodium hydroxide and evaporating the solution to dryness in vacuo.

• Therapeutic Function

  Antibacterial

アセジアスルホンナトリウム 上流と下流の製品情報

アセジアスルホンナトリウム 生産企業

Global(3)Suppliers