ニソキセチン

ニソキセチン 化学特性,用途語,生産方法

• 効能

  抗うつ薬, 選択的ノルアドレナリン再取り込み阻害薬

• 使用

  Antidepressant.

• 一般的な説明

  Nisoxetine is a SNERI and is an antidepressant. Most activityresides in the β-isomer.

• 臨床応用

  Nisoxetine was the initial phenoxyphenylpropylamine synthesized in the Lilly research laboratories during the early 1970s from the rearrangement of an oxygen atom in diphenyhydramine, a diphenylmethoxyethylamine, to a phenoxyphenylpropylamine. Nisoxetine was discovered to be a potent and very selective SNRI, with little affinity for other receptors. It underwent clinical studies as an alternative to Lilly's best-selling antidepressant, nortriptyline, but without the adverse effects associated with the tricyclic secondary amines. It was never marketed, however, because of a greater interest in developing its 4-trifluoromethyl analogue, fluoxetine, an SSRI.

ニソキセチン 上流と下流の製品情報

ニソキセチン 生産企業

Global(7)Suppliers

53179-07-0, ニソキセチン キーワード