(1S,2R)-N1-(tert-ブトキシカルボニル)-1,2-シクロヘキサンジアミン

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Danger

• 危険有害性情報

  H315：皮膚刺激

  H318：重篤な眼の損傷

  H319：強い眼刺激

• 注意書き

  P264：取扱い後は皮膚をよく洗うこと。

  P264：取扱い後は手や顔をよく洗うこと。

  P280：保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。

  P305+P351+P338：眼に入った場合：水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。

(1S,2R)-N1-(tert-ブトキシカルボニル)-1,2-シクロヘキサンジアミン 価格

(1S,2R)-N1-(tert-ブトキシカルボニル)-1,2-シクロヘキサンジアミン 化学特性,用途語,生産方法

• 外観

  白色～ほとんど白色粉末～塊

• 合成

  Triphenylphosphine (14.3 g) was added to a THF (190 ml) solution containing tert-butyl S,2S)-2-hydroxycyclohexyl) carbamate (10.0 g), followed by ice cooling. Diethyl azodicarboxylate (40% in toluene) (24.3 g) and DPPA (15.3 g) were added dropwise to the reaction solution, followed by stirring at room temperature for 1 hour. The reaction solution was left overnight. The solvent was distilled away under reduced pressure. Water was added, and then a 20% sodium hydroxide aqueous solution was added. Then, the organic layers were collected. Water (30 ml) was added to the obtained organic layers, followed by heating to 60 C. A THF (40 ml) solution containing triphenylphosphine (14.3 g) was added dropwise, followed by reflux for 2.5 hours. The solvent was distilled away under ordinary pressure. Toluene was added, and the pH was adjusted with 3M hydrochloric acid to pH=1 or less. Then, the resulting aqueous layers were collected, ethyl acetate was added, and the pH was adjusted with a 20% sodium hydroxide aqueous solution to pH 12. The organic layers were collected and dried over anhydrous sodium sulfate. Light yellow oily matter of tert-butyl ((1S,2R)-2-aminocyclohexyl)carbamate (Carbamic acid, [(1S,2R)-2-aminocyclohexyl]-, 1,1-dimethylethyl ester (9CI))was thus obtained.

(1S,2R)-N1-(tert-ブトキシカルボニル)-1,2-シクロヘキサンジアミン 上流と下流の製品情報

(1S,2R)-N1-(tert-ブトキシカルボニル)-1,2-シクロヘキサンジアミン 生産企業

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(1S,2R)-N1-(tert-ブトキシカルボニル)-1,2-シクロヘキサンジアミン スペクトルデータ(FT-IR)

365996-30-1, (1S,2R)-N1-(tert-ブトキシカルボニル)-1,2-シクロヘキサンジアミン キーワード